Emergence of Vaccine-derived Polioviruses, Democratic Republic of Congo, 2004–2011

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Emergence of Vaccine-derived Polioviruses, Democratic Republic of Congo, 2004–2011

Polioviruses isolated from 70 acute flaccid paralysis patients from the Democratic Republic of Congo (DRC) during 2004-2011 were characterized and found to be vaccine-derived type 2 polioviruses (VDPV2s). Partial genomic sequencing of the isolates revealed nucleotide sequence divergence of up to 3.5% in the viral protein 1 capsid region of the viral genome relative to the Sabin vaccine strain. ...

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ژورنال

عنوان ژورنال: Emerging Infectious Diseases

سال: 2013

ISSN: 1080-6040,1080-6059

DOI: 10.3201/eid1910.130028